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  • Amin, J. & Weiss, D. S. (1993). GABAA receptor needs two homologous domains of the β-subunit for activation by GABA but not pentobarbital. Nature 366, 565569.DOI: 10.1038/366565a0
  • Belelli, D., Callachan, H., Hill-Venning, C., Peters, J. A. & Lambert, J. J. (1996). Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes. British Journal of Pharmacology 118, 563576.
  • Belelli, D., Lambert, J. J., Peters, J. A., Wafford, K. & Whiting, P. J. (1997). The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid. Proceedings of the National Academy of Sciences of the USA 94, 1103111036.
  • Bertrand, D., Devillers-Thiéry, A., Revah, F., Galzi, J.-L., Hussy, N., Mulle, C., Bertrand, S., Ballivet, M. & Changeux, J.-P. (1992). Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain. Proceedings of the National Academy of Sciences of the USA 89, 12611265.
  • Bunch, T. A., Grinblat, Y. & Goldstein, L. S. (1988). Characterisation and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells. Nucleic Acids Research 16, 10431061.
  • Chen, R., Belelli, D., Lambert, J. J., Peters, J. A., Reyes, A. & Lan, N. C. (1994). Cloning and functional expression of a Drosophilaγ-aminobutyric acid receptor. Proceedings of the National Academy of Sciences of the USA 91, 60696073.
  • Davies, P. A., Hannah, M. C., Hales, T. G. & Kirkness, E. F. (1997). Insensitivity to anaesthetic agents conferred by a class of GABAA receptor subunit. Nature 385, 820823.DOI: 10.1038/385820a0
  • Dempster, J. (1997). A new version of the Strathclyde Electrophysiology Software package running within the Microsoft Windows environment. The Journal of Physiology 504.P, 57P.
  • Eger, E. I. II, Koblin, D., Harris, R. A., Kendig, J. J., Pohorille, A., Halsey, M. J. & Trudell, J. R. (1997). Hypothesis: inhaled anesthetics produce immobility and amnesia by different mechanisms at different sites. Anesthesia and Analgesia 84, 915918.
  • Ffrench-Constant, R. H., Mortlock, D. P., Schaffer, C. D., MacIntyre, R. J. & Roush, R. T. (1991). Molecular cloning and transformation of cyclodiene resistance in Drosophila: an invertebrate γ-aminobutyric acid subtype A receptor locus. Proceedings of the National Academy of Sciences of the USA 88, 72097213.
  • Ffrench-Constant, R. H. & Rocheleau, T. A. (1993). Drosophilaγ-aminobutyric acid receptor gene Rdl shows extensive alternative splicing. Journal of Neurochemistry 60, 2323232.
  • Fisher, J. L., Zhang, J. & MacDonald, R. L. (1997). The role of α1 and α6 subtype amino-terminal domains in allosteric regulation of γ-aminobutyric acida receptors. Molecular Pharmacology 52, 714724.
  • Forman, S. A., Miller, K. W. & Yellen, G. (1995). A discrete site for general anesthetics on a postsynaptic receptor. Molecular Pharmacology 48, 574581.
  • Franks, N. P. & Lieb, W. R. (1994). Molecular and cellular mechanisms of general anaesthesia. Nature 367, 607614.DOI: 10.1038/367607a0
  • Haddingham, K. L., Wingrove, P. B., Wafford, K. A., Bain, C., Kemp, J. A., Palmer, K. J., Wilson, A. W., Wilcox, A. S., Sikela, J. M., Ragan, C. I. & Whiting, P. J. (1993). Role of the β subunit in determining the pharmacology of human γ-aminobutyric acid type A receptors. Molecular Pharmacology 44, 12111218.
  • Harris, R. A., Mihic, S. J., Dildy-Mayfield, J. E. & Machu, T. (1995). Actions of anesthetics on ligand-gated ion channels: role of receptor subunit composition. FASEB Journal 9, 14541462.
  • Hill-Venning, C., Belelli, D., Peters, J. A. & Lambert, J. J. (1997). Subunit-dependent interaction of the general anaesthetic etomidate with the γ-aminobutyric acid type A receptor. British Journal of Pharmacology 120, 749756.
  • Hope, A. G., Downie, D. L., Sutherland, L., Lambert, J. J., Peters, J. A. & Burchell, B. (1993). Cloning and functional expression of an apparent splice variant of the murine 5-HT3 receptor A subunit. European Journal of Pharmacology 245, 187192.DOI: 10.1016/0922-4106(93)90128-V
  • Hosie, A. M. & Sattelle, D. B. (1996). Agonist pharmacology of two Drosophila GABA receptor splice variants. British Journal of Pharmacology 119, 15771585.
  • Krasowski, M. D., Finn, S. E., Ye, Q. & Harrison, N. L. (1998b). Trichloroethanol modulation of recombinant GABAA, glycine and GABA ρ receptors. Journal of Pharmacology and Experimental Therapeutics 284, 934942.
  • Krasowski, M. D., Koltchine, V. V., Rick, C. E., Ye, Q., Finn, S. E. & Harrison, N. L. (1998a). Propofol and other intravenous anesthetic agents have sites of action on the gamma-aminobutyric acid type A receptor distinct from that of isoflurane. Molecular Pharmacology 53, 530538.
  • Krishek, B. J., Moss, S. J. & Smart, T. G. (1996). Homomeric β1 γ-aminobutyric acid A receptor-ion channels: evaluation of pharmacological and physiological properties. Molecular Pharmacology 49, 494504.
  • Lambert, J. J., Belelli, D., Pistis, M., Hill-Venning, C. & Peters, J. A. (1997). The interaction of intravenous anaesthetic agents with native and recombinant GABAA receptors. In The GABA Receptors, ed. Enna, S. J. & Bowery, N. G., pp. 121156. Humana Press Inc., Totowa , NJ , USA .
  • Lambert, J. J., Belelli, D., Shepherd, S., Muntoni, A.-L., Pistis, M. & Peters, J. A. (1998). The GABAA receptor: an important locus for intravenous anaesthetic action. In Gases in Medicine: Anaesthesia, 8th BOC Priestley Conference, pp. 121137. Royal Society of Chemistry, London (in the Press)..
  • Little, H. J. (1996). How has molecular pharmacology contributed to our understanding of the mechanism(s) of general anaesthesia? Pharmacology and Therapeutics 69, 3758.DOI: 10.1016/0163-7258(95)02030-6
  • McGurk, K. A., Pistis, M., Belelli, D., Hope, A. G. & Lambert, J. J. (1998). The effect of a transmembrane amino acid on etomidate sensitivity of an invertebrate GABAA receptor. British Journal of Pharmacology 124, 1320.
  • Mihic, S. J., Ye, Q., Wick, M. J., Koltchine, V. V., Krasowski, M. D., Finn, S. E., Mascia, M. P., Valenzula, C. F., Hanson, K. K., Greenblat, E. P., Harris, R. A. & Harrison, N. L. (1997). Sites of alcohol and volatile anaesthetic action on GABAA and glycine receptors. Nature 389, 385388.DOI: 10.1038/38738
  • Minami, K., Wick, M. J., Stern-Bach, Y., Dildy-Mayfield, J. E., Brozowski, S. J., Gonzales, E. L., Trudell, J. R. & Harris, R. A. (1998). Sites of volatile anesthetic action on kainate (glutamate receptor 6) receptors. Journal of Biological Chemistry 273, 82488255.DOI: 10.1074/jbc.273.14.8248
  • Palma, E., Maggi, L., Miledi, R. & Eusebi, F. (1998). Effects of Zn2+ on wild and mutant neuronal α7 nicotinic receptors. Proceedings of the National Academy of Sciences of the USA 95, 1024610250.DOI: 10.1073/pnas.95.17.10246
  • Peters, J. A. & Lambert, J. J. (1997). Anaesthetics in a bind? Trends in Pharmacological Sciences 18, 454455.DOI: 10.1016/S0165-6147(97)01135-8
  • Quinlan, J. J., Homanics, G. E. & Firestone, L. L. (1998). Anesthesia sensitivity in mice that lack the β3 subunit of the γ-aminobutyric acid type A receptor. Anesthesiology 88, 775780.DOI: 10.1097/00000542-199803000-00030
  • Rick, C. E., Ye, Q., Finn, S. E. & Harrison, N. L. (1998). Neurosteroids act on the GABAA receptor at sites on the N-terminal side of the middle of TM2. NeuroReport 9, 379383.
  • Sanna, E., Garau, F. & Harris, R. A. (1995). Novel properties of homomeric β1γ-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbitone. Molecular Pharmacology 47, 213217.
  • Sieghart, W. (1995). Structure and pharmacology of γ-aminobutyric acidA receptor subtypes. Pharmacological Reviews 47, 182234.
  • Smith, G. B. & Olsen, R. W. (1995). Functional domains of GABAA receptors. Trends in Pharmacological Sciences 16, 162168.DOI: 10.1016/S0165-6147(00)89009-4
  • Tanelian, D. L., Kosek, P., Mody, I. & Maciver, M. B. (1993). The role of the GABAA receptor/chloride channel complex in anesthesia. Anesthesiology 78, 757776.
  • Uchida, I., Li, L. & Yang, J. (1997). The role of the GABAA receptor α1 subunit N-terminal extracellular domain in propofol potentiation of chloride current. Neuropharmacology 36, 16111621.DOI: 10.1016/S0028-3908(97)00180-9
  • Wafford, K. A., Thompson, S. A., Thomas, D., Sikela, J., Wilcox, A. S. & Whiting, P. J. (1996). Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha-4 subunit. Molecular Pharmacology 50, 670678.
  • Whiting, P. J., McAllister, G., Vasilatis, D., Bonnert, T. P., Heavens, R. P., Smith, D. W., Hewson, L., O'Donnell, R., Rigby, M. R., Sirinathsinghji, D. J. S., Marshall, G., Thompson, S. A. & Wafford, K. A. (1997). Neuronally restricted RNA splicing regulates the expression of a novel GABAA receptor subunit conferring atypical functional properties. Journal of Neuroscience 17, 50275037.
  • Whiting, P. J., McKernan, R. M. & Wafford, K. A. (1995). Structure and pharmacology of vertebrate GABAA receptor subtypes. International Review of Neurobiology 38, 95138.
  • Wooltorton, J. R. A., Moss, S. J. & Smart, T. G. (1997). Pharmacological and physiological characterization of murine homomeric β3 GABAA receptors. European Journal of Neuroscience 9, 22252235.
  • Ye, Q., Koltchine, V. V., Mihic, S. J., Mascia, M. P., Wick, M. J., Finn, S. E., Harrison, N. L. & Harris, R. A. (1998). Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position α267. Journal of Biological Chemistry 273, 33143319.DOI: 10.1074/jbc.273.6.3314
  • Zhu, W. J., Wang, J. F., Krueger, K. E. & Vicini, S. (1996). δ Subunit inhibits neurosteroid modulators of GABAA receptors. Journal of Neuroscience 16, 66486656.