SEARCH

SEARCH BY CITATION

  • Alberts, A. S., Bouquin, N., Johnston, L. H. & Treisman, R. (1998). Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7. Journal of Biological Chemistry 273, 86168622.
  • Araki, T., Yamano, M., Murakami, T., Wanaka, A., Betz, H. & Tohyama, M. (1988). Localization of glycine receptors in the rat central nervous system: an immunocytochemical analysis using monoclonal antibody. Neuroscience 25, 613624.
  • Baer, K., Essrich, C., Benson, J. A., Benke, D., Bluethmann, H., Fritschy, J.-M. & Lüscher, B. (1999). Postsynaptic clustering of γ-aminobutyric acid type A receptors by the γ3 subunit in vivo. Proceedings of the National Academy of Sciences of the USA 96, 1286012865.
  • Bechade, C., Colin, I., Kirsch, J., Betz, H. & Triller, A. (1996). Expression of glycine receptor α subunits and gephyrin in cultured spinal neurons. European Journal of Neuroscience 8, 429435.
  • Becker, C.-M., Hoch, W. & Betz, H. (1988). Glycine receptor heterogeneity in rat spinal cord during postnatal development. EMBO Journal 7, 37173726.
  • Betz, H. (1998). Gephyrin, a major player in GABAergic postsynaptic membrane assembly? Nature Neuroscience 7, 541543.
  • Boehm, S., Harvey, R. J., von Holst, A., Rohrer, H. & Betz, H. (1998). Glycine receptors in cultured chick sympathetic neurons are excitatory and trigger neurotransmitter release. The Journal of Physiology 504, 683694.
  • Bohlhalter, S., Möhler, H. & Fritschy, J. M. (1994). Inhibitory neurotransmission in rat spinal cord: co-localization of glycine- and GABAA-receptors at GABAergic synaptic contacts demonstrated by triple immunofluorescence staining. Brain Research 642, 5969.
  • Brunn, G. J., Hudson, C. C., Sekulic, A., Williams, J. M., Hosoi, H., Houghton, P. J., Lawrence, J. C., Jr & Abraham, R. T. (1997). Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science 277, 99101.
  • Cabot, J. B., Bushnell, A., Alessi, V. & Mendell, N. R. (1995). Postsynaptic gephyrin immunoreactivity exhibits a nearly one-to-one correspondence with γ-aminobutyric acid-like immunogold-labeled synaptic inputs to sympathetic preganglionic neurons. Journal of Comparative Neurology 356, 418432.
  • Colledge, M. & Froehner, S. C. (1998). Signals mediating ion channel clustering at the neuromuscular junction. Current Opinion in Neurobiology 8, 357363.
  • Craig, A. M., Banker, G., Chang, W., McGrath, M. E. & Serpinskaya, A. S. (1996). Clustering of gephyrin at GABAergic but not glutamatergic synapses in cultured rat hippocampal neurons. Journal of Neuroscience 16, 31663177.
  • Craven, S. E. & Bredt, D. S. (1998). PDZ proteins organize synaptic signaling pathways. Cell 93, 495498.
  • Essrich, C., Lorez, M., Benson, J. A., Fritschy, J. M. & Lüscher, B. (1998). Postsynaptic clustering of major GABAA receptor subtypes requires the γ2 subunit and gephyrin. Nature Neuroscience 7, 563571.
  • Feng, G., Tintrup, H., Kirsch, J., Nichol, M. C., Kuhse, J., Betz, H. & Sanes, J. R. (1998). Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity. Science 282, 13211324.
  • Finkel, T., Theriot, J. A., Dise, K. R., Tomaselli, G. F. & Goldschmidt, C. P. (1994). Dynamic actin structures stabilized by profilin. Proceedings of the National Academy of Sciences of the USA 91, 15101514.
  • Giusetto, M., Kirsch, J., Fritschy, J. M., Cantino, D. & Sassoe-Pognetto, M. (1998). Localization of the clustering protein gephyrin at GABAergic synapses in the main olfactory bulb of the rat. Journal of Comparative Neurology 395, 231244.
  • Godfrey, E. W., Nitkin, R. M., Wallace, B. G., Rubin, L. L. & McMahan, U. J. (1984). Components of Torpedo electric organ and muscle that cause aggregation of acetylcholine receptors on cultured muscle cells. Journal of Cell Biology 99, 615627.
  • Graham, D., Pfeiffer, F., Simler, R. & Betz, H. (1985). Purification and characterization of the glycine receptor of pig spinal cord. Biochemistry 12, 990994.
  • Hanley, J. G., Koulen, P., Bedford, F., Gordon-Weeks, P. R. & Moss, S. J. (1999). The protein MAP-1B links GABAC receptors to the cytoskeleton at retinal synapses. Nature 397, 6669.
  • Hoch, W., Betz, H. & Becker, C.-M. (1989). Primary cultures of mouse spinal cord express the neonatal isoform of the inhibitory glycine receptor. Neuron 3, 339348.
  • Imamura, H., Tanaka, K., Hihara, T., Umikawa, M., Kamei, T., Takahashi, K., Sasaki, T. & Takai, Y. (1997). Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. EMBO Journal 16, 27452755.
  • Johnson, J. L. & Wadman, S. K. (1995). Molybdenum cofactor deficiency and isolated sulfite oxidase deficiency. In The Metabolic and Molecular Bases of Inherited Disease, ed. Scriver, C. R., Beaudet, A. L., Sly, W. S. & Valle, D., pp. 22712283. McGraw-Hill, New York .
  • Jonas, P., Bischofberger, J. & Sandkuhler, J. (1998). Corelease of two fast neurotransmitters at a central synapse. Science 281, 419424.
  • Kavran, J. M., Klein, D. E., Lee, A., Falasca, M., Isakoff, S. J., Skolnik, E. Y. & Lemmon, M. A. (1998). Specificity and promiscuity in phosphoinositide binding by pleckstrin homology (PH) domains. Journal of Biological Chemistry 273, 3049730508.
  • Kins, S., Betz, H. & Kirsch, J. (2000). Collybistin, a novel brain specific GEF, induces submembrane clustering of gephyrin. Nature Neuroscience 3, 2229.
  • Kins, S., Kuhse, J., Laube, B., Betz, H. & Kirsch, J. (1999). Incorporation of a gephyrin-binding motif targets NMDA receptors to gephyrin-rich domains in HEK293 cells. European Journal of Neuroscience 11, 740744.
  • Kirsch, J. (1999). Assembly of signaling machinery at the postsynaptic membrane. Current Opinion in Neurobiology 9, 329335.
  • Kirsch, J. & Betz, H. (1993). Widespread expression of gephyrin, a putative receptor-tubulin linker protein, in rat brain. Brain Research 621, 301310.
  • Kirsch, J. & Betz, H. (1995). The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton. Journal of Neuroscience 15, 41484156.
  • Kirsch, J. & Betz, H. (1998). Glycine-receptor activation is required for receptor clustering in spinal neurons. Nature 392, 717720.
  • Kirsch, J., Kuhse, J. & Betz, H. (1995). Targeting of glycine receptor subunits to gephyrin-rich domains in transfected human embryonic kidney cells. Molecular and Cellular Neuroscience 6, 450461.
  • Kirsch, J., Langosch, D., Prior, P., Littauer, U. Z., Schmitt, B. & Betz, H. (1991). The 93-kDa glycine receptor associated protein binds to tubulin. Journal of Biological Chemistry 266, 2224222245.
  • Kirsch, J., Littauer, U. Z., Schmitt, B., Prior, P., Thomas, L. & Betz, H. (1990). Neuraxin corresponds to a C-terminal fragment of microtubule-associated protein 5 (MAP5). FEBS Letters 262, 259262.
  • Kirsch, J., Malosio, M., Wolters, I. & Betz, H. (1993a). Distribution of gephyrin transcripts in the adult and developing rat brain. European Journal of Neuroscience 5, 11091117.
  • Kirsch, J., Meyer, G. & Betz, H. (1996). Synaptic targeting of ionotropic neurotransmitter receptors. Molecular and Cellular Neuroscience 8, 9398.
  • Kirsch, J., Wolters, I., Triller, A. & Betz, H. (1993b). Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons. Nature 266, 745748.
  • Kneussel, M., Brandstätter, J. H., Laube, B., Stahl, S., Müller, U. & Betz, H. (1999a). Loss of postsynaptic GABAA receptor clustering in gephyrin-deficient mice. Journal of Neuroscience 19, 92899297.
  • Kneussel, M., Hermann, A., Kirsch, J. & Betz, H. (1999b). Hydrophobic interactions mediate binding of the glycine receptor β-subunit to gephyrin. Journal of Neurochemistry 72, 13231326.
  • Koch, M., Kling, C. & Becker, C.-M. (1996). Increased startle responses in mice carrying mutations of glycine receptor. NeuroReport 7, 806808.
  • Kuhse, J., Betz, H. & Kirsch, J. (1995). The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion channel complex. Current Opinion in Neurobiology 5, 318323.
  • Lemmon, M. A., Ferguson, K. M. & Schlessinger, J. (1996). PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface. Cell 85, 621624.
  • Levi, S., Chesnoy-Marchais, D., Sieghart, W. & Triller, A. (1999). Synaptic control of glycine and GABAA receptors and gephyrin expression in cultured motoneurons. Journal of Neuroscience 19, 74347449.
  • Levi, S., Vannier, C. & Triller, A. (1998). Strychnine-sensitive stabilization of postsynaptic glycine receptor clusters. Journal of Cell Science 111, 335345.
  • Malosio, M., Marqueze-Pouey, B., Kuhse, J. & Betz, H. (1991). Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain. EMBO Journal 10, 24012409.
  • Mammoto, A., Sasaki, T., Asakura, T., Hotta, I., Imamura, H., Takahashi, K., Matsuura, Y., Shirao, T. & Takai, Y. (1998). Interactions of drebrin and gephyrin with profilin. Biochemical and Biophysical Research Communications 243, 8689.
  • Mendel, R. R. (1997). Molybdenum cofactor of higher plants: biosynthesis and molecular biology. Planta 203, 399405.
  • Meyer, G., Kirsch, J., Betz, H. & Langosch, D. (1995). Identification of a gephyrin binding motif on the glycine receptor β subunit. Neuron 15, 563572.
  • Pfeiffer, F., Graham, D. & Betz, H. (1982). Purification by affinity chromatography of the glycine receptor of rat spinal cord. Journal of Biological Chemistry 257, 93899393.
  • Prior, P., Schmitt, B., Grenningloh, G., Pribilla, I., Multhaup, G., Beyreuther, K., Maulet, Y., Werner, P., Langosch, D., Kirsch, J. & Betz, H. (1992). Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein. Neuron 8, 11611170.
  • Racca, C., Gardiol, A. & Triller, A. (1997). Dendritic and postsynaptic localizations of glycine receptor α subunit mRNAs. Journal of Neuroscience 17, 16911700.
  • Reichling, D. B., Kyrozis, A., Wang, J. & MacDermott, A. B. (1994). Mechanisms of GABA and glycine depolarization-induced calcium transients in rat dorsal horn neurons. The Journal of Physiology 476, 411421.
  • Reid, T., Bathoorn, A., Ahmadian, M. R. & Collard, J. G. (1999). Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42. Journal of Biological Chemistry 274, 3358733593.
  • Rienitz, A., Grenningloh, G., Hermans-Borgmeyer, I., Kirsch, J., Littauer, U. Z., Prior, P., Gundelfinger, E. D., Schmitt, B. & Betz, H. (1989). Neuraxin, a novel putative structural protein of the rat central nervous system that is immunologically related to microtubule-associated protein 5. EMBO Journal 8, 28792888.
  • Sabatini, D. M., Barrow, R. K., Blackshaw, S., Burnett, P. E., Lai, M. M., Field, M. E., Bahr, B. A., Kirsch, J., Betz, H. & Snyder, S. H. (1999). Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling. Science 284, 11611164.
  • Sabatini, D. M., Lai, M. M. & Snyder, S. H. (1997). Neural roles of immunophilins and their ligands. Molecular Neurobiology 15, 223235.
  • Sassoe-Pognetto, M., Kirsch, J., Grünert, U., Greferath, U., Fritschy, J. M., Möhler, H., Betz, H. & Wässle, H. (1995). Colocalization of gephyrin and GABAA receptor subunits in the rat retina. Journal of Comparative Neurology 357, 114.
  • Schlüter, K., Jokusch, B. M. & Rothkegel, M. (1997). Profilins as regulators of actin dynamics. Biochimica et Biophysica Acta 1359, 97109.
  • Schmidt, A., Bickle, M., Beck, T. & Hall, M. N. (1997). The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell 88, 531542.
  • Schmitt, B., Knaus, P., Becker, C. M. & Betz, H. (1987). The Mr 93000 polypeptide of the postsynaptic glycine receptor complex is a peripheral membrane protein. Biochemistry 26, 805811.
  • Sheng, M. (1996). PDZs and receptor/channel clustering: rounding up the latest suspects. Neuron 17, 575578.
  • Stallmeyer, B., Schwarz, G., Schulze, J., Nerlich, A., Reiss, J., Kirsch, J. & Mendel, R. R. (1999). The neurotransmitter receptor-anchoring protein gephyrin reconstitutes molybdenum cofactor biosynthesis in bacteria, plants, and mammalian cells. Proceedings of the National Academy of Sciences of the USA 96, 13331338.
  • Steward, O. & Halpain, S. (1999). Lamina-specific synaptic activation causes domain-specific alterations in dendritic immunostaining for MAP2 and CAM kinase II. Journal of Neuroscience 19, 78347845.
  • Steward, O., Wallace, C. S., Lyford, G. L. & Worley, P. F. (1998). Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 21, 741751.
  • Todd, A. J., Watt, C., Spike, R. C. & Sieghart, W. (1996). Colocalization of GABA, glycine and their receptors at synapses in the rat spinal cord. Journal of Neuroscience 16, 974982.
  • Triller, A., Cluzeaud, F. & Korn, H. (1987). Gamma-aminobutyric acid-containing terminals can be apposed to glycine receptors at central synapses. Journal of Cell Biology 104, 947956.
  • Triller, A., Sur, C. & Korn, H. (1993). Heterogeneous distribution of glycinergic and GABAergic afferents on an identified central neuron. Journal of Comparative Neurology 338, 8396.
  • Wang, H., Bedford, F. K., Brandon, N. J., Moss, S. J. & Olsen, R. W. (1999). GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton. Nature 397, 6972.
  • Wang, J., Reichling, D. B., Kyrozis, A. & MacDermott, A. B. (1994). Developmental loss of GABA- and glycine-induced depolarization and Ca2+ transients in embryonic rat dorsal horn neurons in culture. European Journal of Neuroscience 6, 12751280.
  • Witke, W., Podtelejnikov, A. V., Di Nardo, A., Sutherland, J. D., Gurniak, C. B., Dotti, C. & Mann, M. (1998). In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly. EMBO Journal 17, 967976.