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Interhemispheric facilitation of the hand motor area in humans

  1. Ritsuko Hanajima,
  2. Yoshikazu Ugawa,
  3. Katsuyuki Machii,
  4. Hitoshi Mochizuki,
  5. Yasuo Terao,
  6. Hiroyuki Enomoto,
  7. Toshiaki Furubayashi,
  8. Yasushi Shiio,
  9. Haruo Uesugi,
  10. Ichiro Kanazawa

Article first published online: 5 AUG 2004

DOI: 10.1111/j.1469-7793.2001.0849h.x

Issue

The Journal of Physiology

The Journal of Physiology

Volume 531, Issue 3, pages 849–859, March 2001

Additional Information

How to Cite

Hanajima, R., Ugawa, Y., Machii, K., Mochizuki, H., Terao, Y., Enomoto, H., Furubayashi, T., Shiio, Y., Uesugi, H. and Kanazawa, I. (2001), Interhemispheric facilitation of the hand motor area in humans. The Journal of Physiology, 531: 849–859. doi: 10.1111/j.1469-7793.2001.0849h.x

Author Information

  1. Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

*Corresponding author Y. Ugawa: Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan., Email: ugawa-tky@umin.ac.jp

Publication History

  1. Issue published online: 5 AUG 2004
  2. Article first published online: 5 AUG 2004
  3. (Received 16 June 2000; accepted after revision 11 November 2000)

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  • Amassian V. E. & Cracco, R. Q. (1987). Human cerebral cortical responses to contralateral transcranial stimulation. Neurosurgery 20, 148–155.
  • Asanuma H. & Okamoto, K. (1959). Unitary study on evoked activity of callosal neurons and its effect on pyramidal tract cell activity on cats. Japanese Journal of Physiology 9, 437–483.
  • Asanuma H. & Okuda, O. (1962). Effects of transcallosal volleys on pyramidal tract cell activity of cat. Journal of Neurophysiology 25, 198–208.
  • Beck P. D. & Kaas, J. H. (1994). Interhemispheric connections in neonatal owl monkeys (Aotus trivirgatus) and galagos (Galago crassicaudatus). Brain Research 651, 57–75.
  • Boroojerdi B., Diefenbach, K. & Ferbert, A. (1996). Transcallosal inhibition in cortical and subcortical cerebral vascular lesions. Journal of the Neurological Sciences 144, 160–170.
  • Brown P., Day, B. L., Rothwell, J. C., Thompson, P. D. & Marsden, C. D. (1991). Intrahemispheric and interhemispheric spread of cerebral cortical myoclonic activity and its relevance to epilepsy. Brain 114, 2333–2351.
  • Castman-Berrevoets C. E., Lemon, R. N., Verburgh, C. A., Bentivoglio, M. & Kuypers, H. G. J. M. (1980). Absence of callosal collaterals derived from rat corticospinal neurons. A study using fluorescent retrograde tracing and electrophysiological techniques. Experimental Brain Research 39, 433–440.
  • Chang H. T. (1953). Cortical response to activity of callosal neurons. Journal of Neurophysiology 16, 117–131.
  • Cracco R. Q., Amassian, V. E., Maccabee, P. J. & Cracco, J. B. (1989). Comparison of human transcallosal responses evoked by magnetic coil and electrical stimulation. Electroencephalography and Clinical Neurophysiology 74, 417–424.
  • Di Lazzaro V., Oliviero, A., Profice, P., Insola, A., Mazzone, P., Tonali, P. & Rothwell, J. C. (1999). Direct demonstration of interhemispheric inhibition of the human motor cortex produced by transcranial magnetic stimulation. Experimental Brain Research 124, 520–524.
  • Ezrokhi V. L., Tarasova, L. Y. & Alexandrov, L. I. (1985). Callosal neurons: Monosynaptic connection between them and their corticofugal projections. Zhurnal Vysshei Nervnoi Deiatelnosti 35, 528–536.
  • Ferbert A., Priori, A., Rothwell, J. C., Day, B. L., Colebatch, J. G. & Marsden, C. D. (1992). Interhemispheric inhibition of the human motor cortex. Journal of Physiology 453, 525–546.
  • Gerloff C., Cohen, L. G., Floeter, M. K., Chen, R., Corwell, B. & Hallett, M. (1998). Inhibitory influence of the ipsilateral motor cortex on responses to stimulation of the human cortex and pyramidal tract. Journal of Physiology 510, 249–259.
  • Hanajima R., Ugawa, Y., Terao, Y., Ogata, K. & Kanazawa, I. (1996). Ipsilateral cortico-cortical inhibition of the motor cortex in various neurological disorders. Journal of the Neurological Sciences 140, 109–116.
  • Hanajima R., Ugawa, Y., Terao, Y., Sakai, K., Furubayashi, T., Machii, K. & Kanazawa, I. (1998). Paired-pulse magnetic stimulation of the human motor cortex: differences among I waves. Journal of Physiology 509, 607–618.
  • Jacobson S. & Marcus, E. M. (1970). The laminar distribution of fibers of the corpus callosum: A comparative study in the rat, cat, rhesus monkey and chimpanzee. Brain Research 24, 517–520.
  • Jacobson S. & Trojanowski, J. Q. (1974). The cell of origin of the corpus callosum in rat, cat and rhesus monkey. Brain Research 74, 149–155.
  • Jenny A. B. (1979). Commissural projections of the cortical hand motor area in monkeys. Journal of Comparative Neurology 188, 137–146.
  • Jones E. G., Coulter, J. D. & Wise, S. P. (1979). Commissural columns in the sensory-motor cortex of monkeys. Journal of Comparative Neurology 188, 113–136.
  • Künzle H. (1975). Bilateral projections from precentral motor cortex to the putamen and other parts of the basal ganglia. An autoradiographic study in macaca fascicularis. Brain Research 88, 195–209.
  • Lassonde M. (1986). The facilitatory influence of the corpus callosum on interhemispheric processing. In Two Hemispheres - One Brain: Functions of the Corpus Callosum, ed. Leporé, F., Ptito, M. & Jasper, H. H., pp. 385–401. Alan R. Liss, Inc., New York
  • Matsunami K. & Hamada, I. (1984). Effects of stimulation of corpus callosum on precentral neuron activity in the awake monkey. Journal of Neurophysiology 52, 676–691.
  • Meyer B.-U., Röricht, S., Gräfinvon Einsiedel H., Kruggel, F. & Weindl, A. (1995). Inhibitory and excitatory interhemispheric transfers between motor cortical areas in normal humans and patients with abnormalities of the corpus callosum. Brain 118, 429–440.
  • Meyer B.-U., Röricht, S. & Woiciechowsky, C. (1998). Topography of fibers in the human corpus callosum mediating interhemispheric inhibition between the motor cortices. Annals of Neurology 43, 360–369.
  • Naitou H., Nakamura, K., Kurosaki, T. & Tamura, Y. (1970). Transcallosal excitatory postsynaptic potentials of fast and slow pyramidal tract cells in cat sensorimotor cortex. Brain Research 19, 299–301.
  • Oldfield R. C. (1971). The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9, 97–113.
  • Sakai K., Ugawa, Y., Terao, Y., Hanajima, R., Furubayashi, T. & Kanazawa, I. (1997). Preferential activation of different I waves by transcranial magnetic stimulation with a figure-eight shaped coil. Experimental Brain Research 113, 24–32.
  • Salerno A. & Georgesco, M. (1996). Interhemispheric facilitation and inhibition studied in man with double magnetic stimulation. Electroencephalography and Clinical Neurophysiology 101, 395–403.
  • Schnitzler A., Kessler, K. R. & Benecke, R. (1996). Transcallosally mediated inhibition of interneurons within human primary motor cortex. Experimental Brain Research 112, 381–391.
  • Shibasaki H., Yamashita, Y. & Kuroiwa, Y. (1978). Electroencephalographic studies of myoclonus. Myoclonus-related cortical spikes and high amplitude somatosensory evoked potentials. Brain 101, 447–460.
  • Thut G., Halsband, U., Regard, M., Mayer, E., Leenders, K. L. & Landis, T. (1997). What is the role of the corpus callosum in intermanual transfer of motor skills? A study of three cases with callosal pathology. Experimental Brain Research 113, 365–370.
  • Ugawa Y., Hanajima, R. & Kanazawa, I. (1993). Interhemispheric facilitation of the hand area of the human motor cortex. Neuroscience Letters 160, 153–155.
  • Werhahn K. J., Fong, J. K. Y., Meyer, B.-U., Priori, A., Rothwell, J. C., Day, B. L. & Thompson, P. D. (1994). The effect of magnetic coil orientation on the latency of surface EMG and single motor unit responses in the first dorsal interosseous muscle. Electroencephalography and Clinical Neurophysiology 93, 138–146.
  • Wilkins D. E., Hallett, M., Berardelli, A., Walshe, T. & Alvarez, N. (1984). Physiologic analysis of the myoclonus of Alzheimer's disease. Neurology 34, 898–903.
  • Wise S. P. (1975). The laminar organization of certain afferent and efferent fiber systems in the rat somatosensory cortex. Brain Research 90, 139–142.
  • Wise S. P. & Jones, E. G. (1976). The organization and postnatal development of the commissural projection of the rat somatic sensory cortex. Journal of Comparative Neurology 168, 313–344.
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