Multiple group principal component analysis is used to investigate the relationship between morphometric characters in inbred and hybrid House mice. Weight is shown to be largely independent of linear size, and character relationships within inbreds are shown to be the same as those within hybrids. Multiple group principal component analysis is largely successful in defining general size and shape components in the Osteometric characters. General size accounts for most of the within-group variation–in spite of the isogenicity, uniform rearing, and uniform age of the mice. Both size and shape are less variable in hybrids than in inbreds. Heterosis is apparent for general size and one component of shape, whilst dominance is widespread amongst the shape components. Canonical analysis is used to investigate inconsistency in the direction of dominance between individual components and the overall direction of dominance.
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