A new species of shrew tenrec in the genus Microgale is described from a series of 12 specimens taken on the south-western slopes of the Tsaratanana Massif in northern Madagascar and is named Microgale jobihely. This new species is distinguished from other named members of this endemic genus by a variety of mensural and discrete morphological characters. Phylogenetic analysis of the mitochondrial ND2 gene supports its recognition as a distinct species and suggests a sister relationship with the much more widespread Microgale cowani. Microgale jobihely appears to be the only member of this genus that is a very localized endemic, and a biogeographic scenario is presented to explain this observation. It is currently known from a small area of forest, outside of the protected areas system, that is faced with considerable anthropogenic pressure.