Annexins

Authors


Author for correspondence:
Julia Davies
Tel: +44 1223 333939
Email: jmd32@cam.ac.uk

Abstract

Contents

 Summary40
I.Introduction40
II.Expression and localization during development41
III.Response to the environment42
IV.Control of subcellular localization42
V.Structural determinants of function43
VI.Activities and possible functions47
VII.Conclusions and prospects49
 Acknowledgements49
 References49

Summary

Annexins are multifunctional lipid-binding proteins. Plant annexins are expressed throughout the life cycle and are under environmental control. Their association or insertion into membranes may be governed by a range of local conditions (Ca2+, pH, voltage or lipid identity) and nonclassical sorting motifs. Protein functions include exocytosis, actin binding, peroxidase activity, callose synthase regulation and ion transport. As such, annexins appear capable of linking Ca2+, redox and lipid signalling to coordinate development with responses to the biotic and abiotic environment. Significant advances in plant annexin research have been made in the past 2 yr. Here, we review the basis of annexin multifunctionality and suggest how these proteins may operate in the life and death of a plant cell.

Ancillary