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Fig. S1 The mass spectrometry (MS) data of trimethylsilyl (TMS) ether for parkeol and isoarborinol.

Fig. S2 Exon-intron structures of oxidosqualene cyclase (OSC) genes from rice.

Fig. S3 Bayesian phylogenetic tree constructed under the GTR + Γ + I substitution model using the MrBayes3.1.2 software.

Fig. S4 Complemental experiment of rice oxidosqualene cyclase (OSC) genes in Saccharomyces cerevisiae Gil77.

Fig. S5 Segmentally duplicated blocks of oxidosqualene cyclases (OSCs) regions in Arabidopsis  thaliana and rice.

Fig. S6 Segmentally duplicated blocks of oxidosqualene cyclases (OSCs) regions in Brachypodium  distachyon and Sorghum  bicolor.

Table S1 List of plant oxidosqualene cyclases (OSCs) involved in this paper

Table S2 Transposable elements in oxidosqualene cyclase (OSC) gene regions in the rice genome

Table S3 Transposable elements in oxidosqualene cyclase (OSC) gene regions in the Sorghum  bicolor genome

Table S4 Transposable elements in oxidosqualene cyclase (OSC) gene regions in the Brachypodium  distachyon genome.

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