The emerging importance of the SPX domain-containing proteins in phosphate homeostasis

Authors

  • David Secco,

    1. Australian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, WA 6009, Australia
    Search for more papers by this author
    • These authors contributed equally to this work.

  • Chuang Wang,

    1. State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, 310058 Hangzhou, China
    Search for more papers by this author
    • These authors contributed equally to this work.

  • Bulak A. Arpat,

    1. Département de Biologie Moléculaire Végétale, Biophore, Université de Lausanne, CH–1015 Lausanne, Switzerland
    Search for more papers by this author
  • Zhiye Wang,

    1. State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, 310058 Hangzhou, China
    Search for more papers by this author
  • Yves Poirier,

    1. Département de Biologie Moléculaire Végétale, Biophore, Université de Lausanne, CH–1015 Lausanne, Switzerland
    Search for more papers by this author
  • Stephen D. Tyerman,

    1. Australian Research Council Centre of Excellence in Plant Energy Biology, School of Agriculture, Food and Wine, Waite Research Institute, University of Adelaide, PMB1, Glen Osmond, SA 5064, Australia
    Search for more papers by this author
  • Ping Wu,

    1. State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, 310058 Hangzhou, China
    2. Joint Research Laboratory in Genomics and Nutriomics, College of Life Sciences, Zhejiang University, 310058 Hangzhou, China
    Search for more papers by this author
  • Huixia Shou,

    1. State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, 310058 Hangzhou, China
    2. Joint Research Laboratory in Genomics and Nutriomics, College of Life Sciences, Zhejiang University, 310058 Hangzhou, China
    Search for more papers by this author
  • James Whelan

    1. Australian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, WA 6009, Australia
    2. Joint Research Laboratory in Genomics and Nutriomics, College of Life Sciences, Zhejiang University, 310058 Hangzhou, China
    Search for more papers by this author

Author for correspondence:
David Secco
Tel: +61 8 6488 44 09
Email: david.secco@uwa.edu.au

Summary

Plant growth and development are strongly influenced by the availability of nutrients in the soil solution. Among them, phosphorus (P) is one of the most essential and most limiting macro-elements for plants. In the environment, plants are often confronted with P starvation as a result of extremely low concentrations of soluble inorganic phosphate (Pi) in the soil. To cope with these conditions, plants have developed a wide spectrum of mechanisms aimed at increasing P use efficiency. At the molecular level, recent studies have shown that several proteins carrying the SPX domain are essential for maintaining Pi homeostasis in plants. The SPX domain is found in numerous eukaryotic proteins, including several proteins from the yeast PHO regulon, involved in maintaining Pi homeostasis. In plants, proteins harboring the SPX domain are classified into four families based on the presence of additional domains in their structure, namely the SPX, SPX-EXS, SPX-MFS and SPX-RING families. In this review, we highlight the recent findings regarding the key roles of the proteins containing the SPX domain in phosphate signaling, as well as providing further research directions in order to improve our knowledge on P nutrition in plants, thus enabling the generation of plants with better P use efficiency.

Ancillary