Social information processing in children and adolescents with neurofibromatosis type 1
Article first published online: 24 FEB 2010
© The Authors. Journal compilation © Mac Keith Press 2010
Developmental Medicine & Child Neurology
Volume 52, Issue 7, pages 620–625, July 2010
How to Cite
HUIJBREGTS, S., JAHJA, R., DE SONNEVILLE, L., DE BREIJ, S. and SWAAB-BARNEVELD, H. (2010), Social information processing in children and adolescents with neurofibromatosis type 1. Developmental Medicine & Child Neurology, 52: 620–625. doi: 10.1111/j.1469-8749.2010.03639.x
- Issue published online: 9 JUN 2010
- Article first published online: 24 FEB 2010
- PUBLICATION DATA Accepted for publication 23rd December 2009. Published online 24th February 2010.
Aim To examine social information processing in children and adolescents with neurofibromatosis type 1 (NF1).
Method Thirty-two children with NF1 (12 males, 20 females; mean age 12y 4mo, SD 4y) and 32 comparison children (12 males, 20 females; mean age 13y 1mo, SD 3y 11mo) completed face recognition, identification of facial emotions (IFE), and matching facial emotions (MFE) tasks. A series of general linear model analyses of variance were used to compare performance between children with NF1 and comparison children.
Results Children with NF1 performed less accurately than comparison children in the face recognition task when faces were presented ‘in profile’ (p=0.05), when fearful expressions had to be identified in IFE (p=0.017), and across conditions in MFE (p=0.009). When quality of cognitive control (i.e. mean standardized scores on tasks measuring working memory and inhibitory control) was introduced to the analyses, differences in face recognition were no longer significant and differences in MFE were largely reduced (p=0.048). Differences in IFE between the comparison group and children with NF1 remained largely intact (fear: p=0.047).
Interpretation Children with NF1 have problems in social information processing, which, in part, appear to be caused by cognitive control deficits. Some of the deficits, however, appear to be caused by deficient bottom-up processing of social signals (e.g. fear recognition).