A potential explanation of some established major risk factors for autism
Version of Record online: 28 FEB 2012
© The Author. Developmental Medicine & Child Neurology © 2012 Mac Keith Press
Developmental Medicine & Child Neurology
Volume 54, Issue 4, pages 301–305, April 2012
How to Cite
JAMES, W. H. (2012), A potential explanation of some established major risk factors for autism. Developmental Medicine & Child Neurology, 54: 301–305. doi: 10.1111/j.1469-8749.2012.04225.x
- Issue online: 9 MAR 2012
- Version of Record online: 28 FEB 2012
- Accepted for publication 8th November 2011. Published online 28th February 2012.
Baron–Cohen hypothesized that a cause of autism in infants is exposure to high concentrations of intrauterine testosterone concentrations. Some of the subsequent research on this hypothesis has focused on the possibility that the source of this testosterone is the fetus; however, this review shows that if the source is taken to be the mother, then many of the established risk factors for autism could be explained. If that were correct, it would follow that high maternally derived intrauterine androgen concentrations may be a major environmental cause of autism.