This article is commented on by Apkon on page 490 of this issue.
A 21-week bone deposition promoting exercise programme increases bone mass in young people with Down syndrome
Article first published online: 13 MAR 2012
© The Authors. Developmental Medicine & Child Neurology © 2012 Mac Keith Press
Developmental Medicine & Child Neurology
Volume 54, Issue 6, pages 552–556, June 2012
How to Cite
GONZÁLEZ-AGÜERO, A., VICENTE-RODRÍGUEZ, G., GÓMEZ-CABELLO, A., ARA, I., MORENO, L. A. and CASAJÚS, J. A. (2012), A 21-week bone deposition promoting exercise programme increases bone mass in young people with Down syndrome. Developmental Medicine & Child Neurology, 54: 552–556. doi: 10.1111/j.1469-8749.2012.04262.x
- Issue published online: 10 MAY 2012
- Article first published online: 13 MAR 2012
- PUBLICATION DATA Accepted for publication 29th December 2011. Published online 13th March 2012.
Aim To determine whether the bone mass of young people with Down syndrome may increase, following a 21-week conditioning training programme including plyometric jumps.
Method Twenty-eight participants with Down syndrome (13 females, 15 males) aged 10 to 19 years were divided into exercise (DS-E; n=14; eight females, six males mean age 13y 8mo, SD 2y 6mo) and non-exercise (DS-NE; n=14; five females, nine males mean age 15y 5mo, SD 2y 6mo) groups. Total and regional (hip and lumbar spine [L1–L4]) bone mineral content (BMC) and total lean mass were assessed by dual energy X-ray absorptiometry at baseline and after a 25-minute training session performed twice a week. Repeated-measures analyses of variation were applied to test differences between pre- and posttraining values for BMC and total lean mass. Differences between increments were studied with the Student’s t-test. Linear regression models were fitted to test independent relationships.
Results After the intervention, higher increments in total and hip BMC, and total lean mass, were observed in the DS-E group (all p<0.05). A time×exercise interaction was found for total lean mass (p<0.05). The increment in total lean mass, height, and Tanner stage accounted for almost for 60% in the increment in total BMC in the DS-NE group (p<0.05).
Interpretation Twenty-one weeks of training have a positive effect on the acquisition of bone mass in young people with Down syndrome.