Neuroanatomical correlates of electrodermal skin conductance responses

Authors

  • DANIEL TRANEL,

    Corresponding author
    1. Department of Neurology, Division of Behavioral Neurology and Cognitive Neuroscience, College of Medicine, University of Iowa, Iowa City
    2. Department of Psychology, University of Iowa, Iowa City
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  • HANNA DAMASIO

    1. Department of Neurology, Division of Behavioral Neurology and Cognitive Neuroscience, College of Medicine, University of Iowa, Iowa City
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  • This research was supported by NINDS Program Project Grant NS 19632.

  • We thank Professor Don Fowles for many helpful suggestions regarding this project and A. Bernstein and three anonymous reviewers for many careful and constructive comments.

Address reprint requests to: Daniel Tranel, Department of Neurology, University of lowa Hospitals and Clinies, lowa City, IA 52242.

Abstract

We studied the electrodermal skin conductance responses (SCRs) of 36 subjects with well-characterized lesions in various regions of the cerebral hemispheres. Several lesion loci were consistently associated with defective electrodermal responding: the ventromedial frontal region (right and left), the right inferior parietal region, and the anterior cingulate gyrus (right and left). Our findings provide direct information regarding neural correlates of skin conductance responses in humans.

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