This study was supported by the Academy of Finland and by EC-Russian Exploratory Collaborative Activity under contract P 9282.
Mismatch negativity to auditory stimulus change recorded directly from the human temporal cortex
Article first published online: 30 JAN 2007
Volume 32, Issue 4, pages 418–422, July 1995
How to Cite
KROPOTOV, J. D., NÄÄÄNEN, R., SEVOSTIANOV, A. V., ALHO, K., REINIKAINEN, K. and KROPOTOVA, O. V. (1995), Mismatch negativity to auditory stimulus change recorded directly from the human temporal cortex. Psychophysiology, 32: 418–422. doi: 10.1111/j.1469-8986.1995.tb01226.x
We thank programmers A. A. Polyakov and V. A. Ponomarey for writing the programs for acquisition and monitoring ERPs and A. D. Anichkov and A. V. Obliapin (all from the Institute of the Human Brain, St. Petersburg) for computing the intracranial electrode locations.
- Issue published online: 30 JAN 2007
- Article first published online: 30 JAN 2007
- (Received February 13, 1995; Accepted March 4, 1995)
- Temporal cortex;
- Intracranial recording;
- Event-related potential (ERP);
- Mismatch negativity;
Mismatch negativity (MMN) is an event-related potential (ERP) component elicited by any discernible change in a repetitive sound even in the absence of attention. Previous studies have established that MMN is generated by change detection in a process comparing the deviant sensory input with the neural memory trace encoding the physical features of the repetitive sound. In the present study, we recorded MMNs to tonal frequency changes directly from the human temporal cortex of patients with electrodes implanted in the brain for diagnosis and therapy. The intracranially recorded MMN was found to be attention independent and modality specific. It was confined to a rather small area in temporal cortex, which was different from the structures where attention-dependent N2 and P3 responses to the frequency change could be recorded.