Christiane Wiesend is now at the Department of Dermatology, University of Freiburg, Freiburg, Germany.
The effect of erroneous responses on response monitoring in patients with major depressive disorder: A study with event-related potentials
Article first published online: 24 SEP 2004
Volume 41, Issue 6, pages 833–840, November 2004
How to Cite
Ruchsow, M., Herrnberger, B., Wiesend, C., Grön, G., Spitzer, M. and Kiefer, M. (2004), The effect of erroneous responses on response monitoring in patients with major depressive disorder: A study with event-related potentials. Psychophysiology, 41: 833–840. doi: 10.1111/j.1469-8986.2004.00237.x
- Issue published online: 24 SEP 2004
- Article first published online: 24 SEP 2004
- (Received November 11, 2003; Accepted April 22, 2003)
- Error related negativity (ERN)/error negativity (Ne);
- Performance feedback;
- Major depressive disorder
Perceived failure is reported to have detrimental effects on subsequent performance in patients with major depressive disorder. We investigated the error-related negativity (ERN)/error negativity (Ne), an electrophysiological correlate of response monitoring, using a 64-channel EEG. Sixteen patients with DSM-IV major depressive disorder and 16 matched controls participated in an Eriksen flanker task with continuous performance feedback that signaled monetary reward. Compared to controls, patients with major depressive disorder showed a less negative ERN/Ne in error trials following error trials. This result might reflect impaired response monitoring processes in major depressive disorder resulting from an underactivity in a central reward pathway and/or a deficit in strategic reasoning.