We thank Christiane Berndt, Julia Putzmann, and Gerald Matzat for their assistance during data collection.
The psychosocial stress-induced increase in salivary alpha-amylase is independent of saliva flow rate
Article first published online: 25 SEP 2006
Volume 43, Issue 6, pages 645–652, November 2006
How to Cite
Rohleder, N., Wolf, J. M., Maldonado, E. F. and Kirschbaum, C. (2006), The psychosocial stress-induced increase in salivary alpha-amylase is independent of saliva flow rate. Psychophysiology, 43: 645–652. doi: 10.1111/j.1469-8986.2006.00457.x
- Issue published online: 25 SEP 2006
- Article first published online: 25 SEP 2006
- (Received April 10, 2006; Accepted July 24, 2006)
- Psychological stress;
- Saliva flow rate;
- Salivary alpha-amylase;
- Salivary amylase output
The stress response of salivary alpha-amylase (sAA) has been suggested as an index for sympathetic nervous system activation. However, concurrent inhibition of the parasympathetic nervous system is discussed as a confounder due to suppression of saliva flow rate. Here we set out to test the influence of stress-induced changes in flow rate on sAA secretion. Twenty-six subjects underwent the Trier Social Stress Test and a control condition. Saliva was sampled by passive drooling or salivettes. Saliva flow rate, sAA levels and output, salivary cortisol, and heart rate variability were measured. Flow rate increased only when sampled by passive drooling. Stress-induced increases in amylase levels were correlated with increases of amylase output but not with flow rate. Results indicate that flow rate is not a confounder of stress-induced sAA activation and suggest that valid measurements of sAA can be obtained by salivettes without the need for assessment of flow rate.