The M100 component of evoked magnetic fields differs by scaling factors: Implications for signal averaging

Authors

Errata

This article is corrected by:

  1. Errata: Erratum Volume 51, Issue 8, 814, Article first published online: 10 July 2014

  • We are grateful to the three anonymous reviewers for constructive criticism, to Profs. Joachim Gross and Ariel Schoenfeld for helpful comments on an earlier version of the manuscript, and to Dr. Artur Matysiak for fruitful discussions. Peter Heil is supported by the Deutsche Forschungsgemeinschaft (SFB-TRR 31 A6).

Address correspondence to: Peter Heil, Leibniz Institute for Neurobiology, Brenneckestraße 6, 39118 Magdeburg, Germany. E-mail: peter.heil@ifn-magdeburg.de

Abstract

MEG and EEG studies of event-related responses often involve comparisons of grand averages, requiring homogeneity of the variances. Here, we examine the possibility, implied by the nature of neural sources and the measuring principles involved, that the M100 component of auditory-evoked magnetic fields of different subjects, hemispheres, to different stimuli, and at different sensors differs by scaling factors. Such a multiplicative model predicts a linear increase in the standard deviation with the mean, and thus would have important implications for averaging and comparing such data. Our analyses, at the sensor and the source level, clearly show that the multiplicative model applies. We therefore propose geometric, rather than arithmetic, averaging of the M100 component across subjects and suggest a novel and superior normalization procedure. Our results question the justification of the common practice of subtracting arithmetic grand averages.

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