The authors thank Philippe Stébenne, Silvana Barone, Nadine Bekkouche, and Sandra Pelaez for help with data collection. Funding for the collection of data was provided by operating grants from the Heart and Stroke Foundation of Quebec and the Canadian Institutes of Health Research (CIHR: MOP79445 and MOP89965). Personal support was received for Gordon from the Canadian Hypertension Society (summer studentship), le Fonds de la recherche en santé du Québec (FRSQ; master's fellowship), and a Vanier Ph.D. fellowship. Salary support was received for Bacon and Lavoie (chercheur boursiers) from the FRSQ and from a CIHR New Investigator Award (Bacon).
The effect of major depression on postexercise cardiovascular recovery
Article first published online: 1 AUG 2011
Copyright © 2011 Society for Psychophysiological Research
Volume 48, Issue 11, pages 1605–1610, November 2011
How to Cite
Gordon, J. L., Ditto, B., Lavoie, K. L., Pelletier, R., Campbell, T. S., Arsenault, A. and Bacon, S. L. (2011), The effect of major depression on postexercise cardiovascular recovery. Psychophysiology, 48: 1605–1610. doi: 10.1111/j.1469-8986.2011.01232.x
- Issue published online: 5 OCT 2011
- Article first published online: 1 AUG 2011
- (Received November 7, 2010; Accepted May 24, 2011)
- Heart rate (HR);
- Blood pressure (BP);
- Cardiovascular recovery;
- Autonomic nervous system (ANS)
Major depressive disorder (MDD) is associated with increased cardiovascular (CV) mortality. Dysfunctional autonomic control of the CV system may represent a mechanism explaining this relationship. Poor CV recovery after exercise, indicative of dysfunctional autonomic control of the CV system, predicts CV events and death. This is the first study to examine the association between MDD and postexercise CV recovery. Some 886 patients underwent exercise stress tests. Heart rate (HR), systolic blood pressure, and diastolic blood pressure were measured at rest, peak exercise, 1 min, and 5 min after exercise. Patients with MDD had slower HR recovery (p=.026) 1 min after exercise than non-MDD patients. No other effects of MDD were found. MDD is accompanied by a dysregulation in autonomic control of exercise-related CV recovery, suggesting that depressed individuals have a slow parasympathetic recovery from exercise.