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FACTORS AFFECTING MYOMETRIAL ACTIVITY DURING PREGNANCY
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1972.tb11875.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 79, Issue 11, pages 985–989, November 1972
Additional Information
How to Cite
Brummer, H. C. and Collins, W. P. (1972), FACTORS AFFECTING MYOMETRIAL ACTIVITY DURING PREGNANCY. BJOG: An International Journal of Obstetrics & Gynaecology, 79: 985–989. doi: 10.1111/j.1471-0528.1972.tb11875.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
The relationship between the concentration of progesterone in peripheral venous plasma and in strips of myometrial tissue from 17 pregnant women has been studied. In addition, the sensitivity of 39 myometrial strips to various stimulants was examined by an in vitro technique. The responses were assessed in relation to the endogenous levels of progesterone, length of gestation, and parity of the subject. The results indicate that although the levels of progesterone in both peripheral venous plasma and myometrium rise during pregnancy there is no apparent correlation between the two. Myometrial sensitivity to Syntocinon and prostaglandins E1 and E2 is not dependent upon the level of progesterone in either the myometrium or peripheral venous plasma. Myometrial strips removed at term from multigravidae were more responsive to these drugs than those from primigravidae, but during the second trimester there was no statistically significant difference between the two.