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Summary

Patients considered to be at extra risk of fetal loss because of previous history were assessed throughout pregnancy for hormone deficiency by cervical mucus smears, vaginal cytology and total oestrogen excretion. There was a significantly higher incidence of light-for-dates babies when cervical mucus ferning was noted early in pregnancy and persisted or recurred after 16 weeks. Early detection of‘placental insufficiency’by ferning in the mucus would allow closer study of the factors which impair intrauterine growth.