HUMAN PLACENTAL LACTOGEN LEVELS IN PRE-ECLAMPSIA

  1. A. T. Letchworth,
  2. T. Chard

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1972.tb12900.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 79, Issue 8, pages 680–683, August 1972

Additional Information

How to Cite

Letchworth, A. T. and Chard, T. (1972), HUMAN PLACENTAL LACTOGEN LEVELS IN PRE-ECLAMPSIA. BJOG: An International Journal of Obstetrics & Gynaecology, 79: 680–683. doi: 10.1111/j.1471-0528.1972.tb12900.x

Author Information

  1. Departments of Obstetrics and Gynaecology, and Chemical Pathology, St. Bartholomew's Hospital Medical College, London, E.C.I

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005

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Summary

A prospective study has been carried out on human placental lactogen (HPL) levels in pre-eclampsia. The general conclusions were as follows: (1) the levels were lower than those in normal subjects; (2) the levels in mild pre-eclampsia were lower than those in the moderate and severe cases; (3) the levels were lower in multipara than in primipara. The influence of severity and parity may partly explain the discrepancies encountered in earlier studies. Low levels of HPL were found in patients with fetal complications. However, since similar levels may be found in pre-eclampsia without such complications, it was not possible to reach definite conclusions on the value of HPL determinations as a predictor of fetal well-being. The results indicate the need for further investigation of the prognostic significance of HPL levels within sub-groups of patients with pre-eclampsia.

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