Senior Lecturer, Department of Obstetrics and Gynaecology, University of Newcastle Upon Tyne.
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PLASMA BIOCHEMISTRY IN RELATION TO OEDEMA OF PREGNANCY
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1972.tb12918.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 79, Issue 9, pages 769–776, September 1972
Additional Information
How to Cite
Robertson, E. G. and Cheyne, G. A. (1972), PLASMA BIOCHEMISTRY IN RELATION TO OEDEMA OF PREGNANCY. BJOG: An International Journal of Obstetrics & Gynaecology, 79: 769–776. doi: 10.1111/j.1471-0528.1972.tb12918.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
Biochemical changes were measured serially throughout pregnancy in 83 women. The fall in total osmolality observed was unrelated to the development of oedema and there was little change in the levels of major electrolytes and urea with pregnancy. Decreased colloid osmotic pressure values were found, and they closely followed the changes in both total protein and serum albumin values. The degree of fall of these values appeared to be more important in the genesis of oedema than the absolute level reached. Changes in haematological indices were unrelated to the presence of oedema but a change in red cell fragility was found which appeared to be related to variations in colloid osmotic pressure. This change seemed to be of physiological rather than pathological significance.