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ON THE PATHOGENESIS OF PLACENTAL INFARCTS IN PRE-ECLAMPSIA
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1972.tb12922.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 79, Issue 9, pages 794–799, September 1972
Additional Information
How to Cite
Brosens, I. and Renaer, M. (1972), ON THE PATHOGENESIS OF PLACENTAL INFARCTS IN PRE-ECLAMPSIA. BJOG: An International Journal of Obstetrics & Gynaecology, 79: 794–799. doi: 10.1111/j.1471-0528.1972.tb12922.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
Placental bed spiral arteries underlying placental infarcts were studied in a hysterectomy specimen with the placenta in situ and in placental bed biopsies from cases of severe pre-eclampsia. The spiral arteries supplying infarcted placentae differed from normal spiral arteries in two important features; first, in the failure of trophoblast infiltration and concomitant physiological changes of the myometrial segment of the spiral artery and, second, in the appearance in this segment of hypertensive, occlusive vascular lesions. Although placental infarction is apparently a direct result of the occlusive hypertensive lesions in the spiral arteries, it is also to be considered as the ultimate evidence of failure of adequate placentation.