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OVARIAN CARCINOMA: IMPROVEMENT IN SURVIVAL TIME AFTER CHEMOTHERAPY
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1972.tb14199.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 79, Issue 6, pages 550–554, June 1972
Additional Information
How to Cite
Nye, E. B. (1972), OVARIAN CARCINOMA: IMPROVEMENT IN SURVIVAL TIME AFTER CHEMOTHERAPY. BJOG: An International Journal of Obstetrics & Gynaecology, 79: 550–554. doi: 10.1111/j.1471-0528.1972.tb14199.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
A series of 667 cases of ovarian cancer have been studied; 176 patients had triethylene thiophosphoramide chemotherapy and were matched with controls which had not received chemotherapy.
In the group with widespread cancer a significantly greater number of treated patients than controls were alive at all times of analysis up to three years after operation. Possible sources of bias have been critically analyzed. Despite close matching, and the apparently favourable result, it was not possible to prove that chemotherapy prolongs survival and a large-scale prospective controlled trail of chemotherapy in ovarian cancer is still necessary and would be justifiable.