ORAL CONTRACEPTION AND LIVER FLUKE DISEASE
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1972.tb14219.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 79, Issue 7, pages 657–660, July 1972
Additional Information
How to Cite
Chulacharit, E., Petchakit, V. and Rosenfield, A. G. (1972), ORAL CONTRACEPTION AND LIVER FLUKE DISEASE. BJOG: An International Journal of Obstetrics & Gynaecology, 79: 657–660. doi: 10.1111/j.1471-0528.1972.tb14219.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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- Cited By
Summary
Opisthorchis Viverrini (liver fluke) infestation is endemic in certain parts of Thailand, where the incidence is as high as 90 per cent. Although the disease is essentially benign in man, there has been concern that oral contraception may be contra-indicated in patients with this disease. In the present study no laboratory differences were found between a group of oral contraceptive users with positive stools and those with negative stools. The only minor abnormality found after oral contraceptive use was a slight increase in the bromsulphthalein retention values in both groups of patients as compared to a control group using intrauterine devices. No case of jaundice was seen in either group of pill acceptors. It is concluded that oral contraceptives are safe in patients with this parasitic disease.

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