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Summary

Estimations of levels of heat-stable alkaline phosphatase in amniotic fluid and maternal serum were performed in 78 normal and 27 pre-eclamptic pregnant mothers. The concentration of this enzyme was greater in maternal serum than in amniotic fluid in both normal pregnancy and pre-eclampsia, and the correlation between maternal serum HSAP and liquor HSAP in both groups was statistically significant. Mean values of liquor HSAP were higher in pre-eclampsia than in normal pregnancy at corresponding periods of gestation, and in both groups there was an abrupt rise in levels after the 36th week of pregnancy