THE RELATIONSHIP OF THE POSTPARTUM RISE IN SEROMUCOID TO PRIMIGRAVID PLACENTAL WEIGHT
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1972.tb15745.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 79, Issue 1, pages 36–39, January 1972
Additional Information
How to Cite
Good, W., Hancock, K. W. and Macdonald, H. N. (1972), THE RELATIONSHIP OF THE POSTPARTUM RISE IN SEROMUCOID TO PRIMIGRAVID PLACENTAL WEIGHT. BJOG: An International Journal of Obstetrics & Gynaecology, 79: 36–39. doi: 10.1111/j.1471-0528.1972.tb15745.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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- Cited By
Summary
The postpartum rise in seromucoid, which is an heterogenous acid-soluble glycoprotein sub-fraction, is related to placentalweight in primigravidae but not in multigravidae. This observation supports the view that primigravidae, who have had no previous exposure to paternal histocompatibility antigens, depend on glycoprotein to mask the trophoblast from the cellular immune response. With previous exposure to paternal histocompatibility antigens, as in multigravidae, the maternal antibodies so formed may coat the trophoblast and thus reduce the need for a covering of nonspecific glycoprotein.

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