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Summary

The mean random blood concentration of non-glucose reducing substances is lower in 540 pregnant women than in 56 non-pregnant controls. The mean blood levels of non-glucose reducing substances were also measured during a 50 g. oral glucose tolerance test on 412 women in pregnancy and the puerperium and were little different from random levels; the levels at 2½ hours were lower than those fasting. A significant negative correlation of blood glucose levels and those of non-glucose reducing substances may be a technical artefact, although a functional relationship cannot be excluded. The levels of non-glucose reducing substances do not appear to increase during pregnancy, but the range of values is so wide, and at present, unpredictable that blood glucose should be measured by a method for “true” glucose in pregnant women as in others.