Research Fellow, King's College Hospital, Denmark Hill, London, S.E.5.
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THE USE OF DIAZEPAM AND HYDRALLAZINE IN THE TREATMENT OF SEVERE PRE-ECLAMPSIA
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1972.tb15792.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 79, Issue 3, pages 250–254, March 1972
Additional Information
How to Cite
Joyce, D. N. and Kenyon, V. G. (1972), THE USE OF DIAZEPAM AND HYDRALLAZINE IN THE TREATMENT OF SEVERE PRE-ECLAMPSIA. BJOG: An International Journal of Obstetrics & Gynaecology, 79: 250–254. doi: 10.1111/j.1471-0528.1972.tb15792.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
An intravenous infusion of diazapan and hydrallazine was given to 52 patients with severe pre-eclampsia in labour. The results of this treatment have been compared with those from a similar group of patients treated with a lytic cocktail regime or rectal Avertin (tribromethanol). Diazepam and hydrallazine gave significantly better control of blood pressure than the lytic and Avertin regimes without producing any adverse reactions other than a tendency to hypothermia in the newborn. No patient developed eclampsia while being treated with diazepan and hydrallazine, but one patient had a fit while being treated with a lytic cocktail and had a further fit after subsequent Avertin treatment.