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Summary

One hundred and sixty-four consecutive cases of malignant disease of the vulva have been analyzed with regard to their clinical features and treatment. Delay in seeking treatment or being referred to a specialist was common. The lesions were staged by three different methods and the classification proposed by the International Federation of Obstetrics and Gynaecology (FIGO) showed the closest correlation with the five-year survival rate. In general, vulvectomy with simultaneous bilateral inguinal and femoral lymphadenectomy is the treatment of choice but the extent of the operation should be tailored to the individual patient. With a small lesion (less than 2 cm. in diameter) and in the absence of suspiciously enlarged lymph nodes in the groin a more limited procedure might be justified particularly if the patient is a poor surgical risk. In the few cases with spread of neoplasm to the vatina or anus, pelvic lymphadenectomy will be indicated and possibly some from of exenteration.