BIOCHEMICAL AND HAEMATOLOGICAL CHANGES DURING THE INDUCTION OF LABOUR AT TERM WITH OXYTOCIN, PROSTAGLANDIN E2 AND PROSTAGLANDIN F2α

  1. A. H. Gowenlock Consultant Chemical Pathologist1,
  2. D. S. Taylor Senior Registrar2,
  3. J. H. Sanderson M.R.C. Clinical Research Fellow3

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1975.tb00622.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 82, Issue 3, pages 215–220, March 1975

Additional Information

How to Cite

Gowenlock, A. H., Taylor, D. S. and Sanderson, J. H. (1975), BIOCHEMICAL AND HAEMATOLOGICAL CHANGES DURING THE INDUCTION OF LABOUR AT TERM WITH OXYTOCIN, PROSTAGLANDIN E2 AND PROSTAGLANDIN F2α. BJOG: An International Journal of Obstetrics & Gynaecology, 82: 215–220. doi: 10.1111/j.1471-0528.1975.tb00622.x

Author Information

  1. 1

    United Manchester Hospitals

  2. 2

    St. Mary's Hospitals, Manchester

  3. 3

    Department of Clinical Haematology, Royal Infirmary, Manchester

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005

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Summary

A total of 75 patients had labour induced near term using intravenous oxytocin, prostaglandin E, or prostaglandin Fza. Biochemical and haematological investigations were performed to assess hepatic, renal and adrenocortical function and changes in platelet adhesiveness. In doses which were similarly effective in inducing labour, both prostaglandins were without the water-retaining effect of oxytocin. Adrenocortical stimulation was greatest with oxytocin. No difference between these agents was observed for the other measurements made.

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