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AMNIOTIC FLUlD α1 FETOPROTEIN IN THE DIAGNOSIS OF NEURAL TRACT MALFORMATIONS
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1975.tb00630.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 82, Issue 4, pages 257–261, April 1975
Additional Information
How to Cite
Stewart, C. R., Ward, A. M. and Lorber, J. (1975), AMNIOTIC FLUlD α1 FETOPROTEIN IN THE DIAGNOSIS OF NEURAL TRACT MALFORMATIONS. BJOG: An International Journal of Obstetrics & Gynaecology, 82: 257–261. doi: 10.1111/j.1471-0528.1975.tb00630.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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- Cited By
Summary
Amniotic fluid α1 fetoprotein levels were determined in 400 pregnancies. The normal range for α1 fetoprotein in amniotic fluid was defined by 350 samples from normal pregnancies. Elevated levels of α1 fetoprotein were detected in 17 out of 18 pregnancies which gave rise to infants with neural tract abnormalities. The significance of this test in the antenatal diagnosis of neural tract abnormalities is discussed together with the possible reasons for “false negative” and “false positive” results. There were no complications in an individual series of 105 consecutive amniocenteses.