THE PROGNOSTIC VALUE OF HUMAN PLACENTAL LACTOGEN (HPL) LEVELS IN THREATENED ABORTION
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1975.tb00639.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 82, Issue 4, pages 303–309, April 1975
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How to Cite
Gartside, M. W. and Tindall, V. R. (1975), THE PROGNOSTIC VALUE OF HUMAN PLACENTAL LACTOGEN (HPL) LEVELS IN THREATENED ABORTION. BJOG: An International Journal of Obstetrics & Gynaecology, 82: 303–309. doi: 10.1111/j.1471-0528.1975.tb00639.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
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Summary
The value of a single HPL, estimation in serum was assessed in 337 patients with a threatened abortion between 7 and 27 weeks gestation. Serial assays were subsequently performed on 75 of these. A scheme is proposed whereby an HPL result can be given a “favourable”, “equivocal” or “unfavourable” prognosis according to its level. Using this scheme a correct prognosis was obtained in 86 per cent of cases between 9 and 19 weeks gestation while an incorrect prognosis was obtained in 3 per cent of cases. There appeared to be little prognostic value after 19 weeks gestation though prior to 9 weeks the results were sufficiently promising to suggest that a more sensitive assay would be useful.

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