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CARBOHYDRATE-INDUCED LIPOGENESIS IN THE HUMANPLACENTA OF NORMAL AND DIABETIC PREGNANCIES
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1975.tb00672.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 82, Issue 6, pages 471–475, June 1975
Additional Information
How to Cite
Coltart, T. M. and Bateman, C. (1975), CARBOHYDRATE-INDUCED LIPOGENESIS IN THE HUMANPLACENTA OF NORMAL AND DIABETIC PREGNANCIES. BJOG: An International Journal of Obstetrics & Gynaecology, 82: 471–475. doi: 10.1111/j.1471-0528.1975.tb00672.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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- Cited By
Summary
Using in vitro incubation, human placental slices have been shown to synthesize lipid from 14C fructose, but to a lesser extent than from 14C glucose. Diabetic placentae did not incorporate more of either sugar into lipid than did placentae from normal pregnancies; nor did insulin in the incubation medium enhance lipogenesis. There was a correlation between the extent of incorporation of 14C fructose and 14C glucose into triglyceride, suggesting a linked enzyme system for phosphorylation of the two hexoses.