Present appointment: Senior Lecturer and Consultant Obstetrician and Gynaecologist, Department of Obstetrics and Gynaecology, University College Hospital, Ibadan, Nigeria.
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ROLE OF SEX-HORMONE-BINDING GLOBULIN IN HORMONAL CHANGES AND AMENORRHOEA IN THYROTOXIC WOMEN
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1975.tb00686.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 82, Issue 7, pages 557–561, July 1975
Additional Information
How to Cite
Akande, E. O. and Anderson, D. C. (1975), ROLE OF SEX-HORMONE-BINDING GLOBULIN IN HORMONAL CHANGES AND AMENORRHOEA IN THYROTOXIC WOMEN. BJOG: An International Journal of Obstetrics & Gynaecology, 82: 557–561. doi: 10.1111/j.1471-0528.1975.tb00686.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
Plasma levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), oestrogen, testosterone and sex-hormone-binding globulin (SHBG) were determined in 15 thyrotoxic women in the reproductive age before and after treatment with carbimazole. The levels of these hormones and SHBG were compared with those of 12 euthyroid healthy female volunteers of comparable age and parity. Plasma gonadotrophins (LH and FSH), oestrogen, testosterone and SHBG were all markedly elevated in thyrotoxic subjects but became normal when the euthyroid state and normal menstruation were restored after treatment. From the results a hypothesis is suggested which relates the hormonal disturbance primarily to a thyroid hormone-induced rise in SHBG levels.