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EFFECT OF BROMOCRIPTINE AND CHLOROTRIANISENE ON TNHIBITION OF LACTATION AND SERUM PROLACTIN A COMPARATIVE DOUBLE-BLIND STUDY
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1975.tb00718.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 82, Issue 9, pages 755–759, September 1975
Additional Information
How to Cite
Utian, W. H., Begg, G., Vinik, A. I., Paul, M. and Shuman, L. (1975), EFFECT OF BROMOCRIPTINE AND CHLOROTRIANISENE ON TNHIBITION OF LACTATION AND SERUM PROLACTIN A COMPARATIVE DOUBLE-BLIND STUDY. BJOG: An International Journal of Obstetrics & Gynaecology, 82: 755–759. doi: 10.1111/j.1471-0528.1975.tb00718.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
A double-blind study to compare the effect of 2-Br-alpha-ergocryptine (bronio-criptine, CB 154, Sandoz) an ergot alkaloid with chlorotrianisene (Tace, Mer-National) on the inhibition of postpartum lactation was carried out in 38 women. At the dosages selected bromocriptine was more effective than chlorotrianisene in inhibiting lactation. Furthermore, bromocriptine significantly reduced serum prolactin levels to low normal values by the seventh day of treatment, whereas chlorotrianisene did not alter the normal progressive reduction in prolactin postpartum. Neither drug had significant toxic effects.