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Summary

A synthetic compound, 2a, 2b dihomo 15 (S) 15 methyl prostaglandin F methyl ester given 8 hourly by intramuscular injection was used to terminate pregnancies in 72 patients with a missed abortion, intrauterine fetal death, molar or anencephalic pregnancies. Treatment was successful in all cases. A 4 mgdose of loperamide given orally at 15 to 30 minutes before the injection of prostaglandin analogue prevented diarrhoea as a side effect.