1471-0528/asset/BJO_left.gif?v=1&s=0fb87361cdb6be25fdf05019eed6d47f5143f610)
1471-0528/asset/olbannerright.gif?v=1&s=3892ef16ff18d6834c302faf85268a49f5fc588f)
THE FETAL MEMBRANES AS A POSSIBLE SOURCE OF AMNIOTIC FLUID PROSTAGLANDINS
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1976.tb00797.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 83, Issue 2, pages 146–151, February 1976
Additional Information
How to Cite
Keirse, M. J. N. C. and Turnbull, A. C. (1976), THE FETAL MEMBRANES AS A POSSIBLE SOURCE OF AMNIOTIC FLUID PROSTAGLANDINS. BJOG: An International Journal of Obstetrics & Gynaecology, 83: 146–151. doi: 10.1111/j.1471-0528.1976.tb00797.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
Biosynthesis and metabolism of prostaglandins was studied in human amniotic and chorionic membranes obtained at term. Using specific in vitro methods it was demonstrated that the fetal membranes contain an organization of enzymes regulating both synthesis and degradation of prostaglandins. Differentiation between amnion and chorion showed that virtually all of the biosynthesis and metabolism occurred in the chorion, whereas enzymatic activities in the amnion were negligible or low. The results suggest a high turnover of prostaglandins in the chorion, and its importance as a source of prostaglandins found in amniotic fluid is discussed.