A SERIAL STUDY OF PREGNANCY PROTEINS IN PRIMIGRAVIDAE

  1. C. M. Towler1,
  2. V. Jandial1,
  3. C. H. W. Horne1,
  4. H. Bohn2

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1976.tb00844.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 83, Issue 5, pages 368–374, May 1976

Additional Information

How to Cite

Towler, C. M., Jandial, V., Horne, C. H. W. and Bohn, H. (1976), A SERIAL STUDY OF PREGNANCY PROTEINS IN PRIMIGRAVIDAE. BJOG: An International Journal of Obstetrics & Gynaecology, 83: 368–374. doi: 10.1111/j.1471-0528.1976.tb00844.x

Author Information

  1. 1

    Departments of Pathology and Obstetrics and Gynaecology Aberdeen University Medical School Foresterhill, Aberdeen, Scotland

  2. 2

    Behringwerke AG, Marburg, Lahn West Germany

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005

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Summary

The plasma concentrations of four ‘pregnancy proteins' and three steroid hormones have been measured throughout pregnancy in 15 primigravidae. Two of the proteins, human placental lactogen (HPL) and pregnancy-specific β1-glycoprotein (PS βG), are specific for pregnancy and correlate well with the stage of gestation. It is suggested that measurement of PSβG may be useful in assessing feto-placental wellbeing. Neither of the pregnancy-associated proteins, steroid-binding β-globulin (SB βG) and pregnancy-associated α2-glycoprotein (α2-PAG), correlated with the length of gestation although, near term, plasma α2-PAG levels appeared to be related to fetal weight. In addition, no correlation has been demonstrated between placental or fetal weight and any of the pregnancy-specific proteins or steroid hormones studied.

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