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Summary

An analysis of 155 patients with endometrial carcinoma, first seen more than five years ago, shows that 31 per cent died with tumour. Trans-coelomic spread of tumour was the most frequent cause of death and occurred in 13·6 per cent of all patients and in 17·1 per cent of those who were operable. A second important cause of death was haematogenous spread of tumour (6·5 per cent). Local pelvic recurrence was the cause of death in 25 per cent of those who did not survive, and local spread was found in 2·2 per cent of operable patients. A rational approach to therapy for endometrial carcinoma is suggested.