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SERUM PROLACTIN AND THE SUPPRESSION OF LACTATION
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1976.tb00912.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 83, Issue 9, pages 679–682, September 1976
Additional Information
How to Cite
Weinstein, D., Ben-David, M. and Polishuk, W. Z. (1976), SERUM PROLACTIN AND THE SUPPRESSION OF LACTATION. BJOG: An International Journal of Obstetrics & Gynaecology, 83: 679–682. doi: 10.1111/j.1471-0528.1976.tb00912.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
Baromocriptine (2 bromo-α-ergocryptine), stilboestrol, clomiphene citrate, testosterone propionate and a placebo were given to 75 postpartum women for the suppression of puerperal lactation. An additional 15 women who breast-fed their babies served as a control group. Blood samples were taken for the determination of serum prolactin levels by a specific homologous double antibody radioimmuno-assay. Concurrently, the clinical effectiveness of the various treatments was assessed. High levels of prolactin were found at the time of delivery. Bromocriptine effectively reduced serum prolactin and prevented lactation; stilboestrol increased serum prolactin and partially suppressed lactation; clomiphene citrate and testosterone propionate both lowered serum prolactin levels and partially suppressed lactation. The placebo showed almost no effect on serum prolactin. It appeared that bromocriptine was the drug of choice in the suppression of puerperal lactation.