THE EFFECT OF LABOUR ON ACTH AND CORTISOL LEVELS IN AMNIOTIC FLUID AND MATERNAL BLOOD

  1. R. Tuimala,
  2. A. Kauppila,
  3. L. Rönnberg,
  4. R. Jouppila,
  5. J. Haapalahti

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1976.tb00917.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 83, Issue 9, pages 707–710, September 1976

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How to Cite

Tuimala, R., Kauppila, A., Rönnberg, L., Jouppila, R. and Haapalahti, J. (1976), THE EFFECT OF LABOUR ON ACTH AND CORTISOL LEVELS IN AMNIOTIC FLUID AND MATERNAL BLOOD. BJOG: An International Journal of Obstetrics & Gynaecology, 83: 707–710. doi: 10.1111/j.1471-0528.1976.tb00917.x

Author Information

  1. Department of Obstetrics and Gynaecology and Department of Anaesthesiology, University of Oulu and Laboratory of Deaconess Institute, Oulu, Finland

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005

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Summary

Levels of adrenocorticotrophic hormone (ACTH) and cortisol were measured in amniotic fluid during labour and in maternal blood during and after labour. There was a significant rise of maternal ACTH and cortisol levels during labour and a significant decrease after delivery in all 14 patients studied. There were no significant changes in amniotic fluid ACTH and cortisol levels during labour. The initial level of ACTH in amniotic fluid (162·7 pg/ml) was higher than that in maternal circulation (120·2 pg/ml). The correlation between maternal and amniotic fluid ACTH was not significant while the corresponding correlation for cortisol values was.

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