MEASUREMENT OF INTERVILLOUS AND MYOMETRIAL BLOOD FLOW BY AN INTRAVENOUS 133Xe METHOD

  1. A. Rekonen,
  2. H. Luotola,
  3. M. Pltkänen,
  4. J. Kuikka,
  5. T. Pyörälä

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1976.tb00921.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 83, Issue 9, pages 723–728, September 1976

Additional Information

How to Cite

Rekonen, A., Luotola, H., Pltkänen, M., Kuikka, J. and Pyörälä, T. (1976), MEASUREMENT OF INTERVILLOUS AND MYOMETRIAL BLOOD FLOW BY AN INTRAVENOUS 133Xe METHOD. BJOG: An International Journal of Obstetrics & Gynaecology, 83: 723–728. doi: 10.1111/j.1471-0528.1976.tb00921.x

Author Information

  1. Department of Obstetrics and Gynaecology and Isotope Laboratory Central Finland Central Hospital, SF-40620 Jyväskylä 62, Finland

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005

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Summary

A new ‘non-invasive’ method for measuring intervillous and myometrial blood flow is presented. After 2 mCi of 133Xe in physiological saline was injected intravenously the patient held her breath for 20 seconds. The tracer entered the placenta as a short bolus and its removal was followed with a scintillation detector. Intervillous and myometrial blood flow per unit volume was calculated from the two-exponential curve. The mean ±SD intervillous flow in normal pregnancy was 135±49 ml/minute/100 ml, the corresponding half time being 0·56±0·16 minutes. The myometrial flow was 7 ·7±2·5 ml/minute/100 g. The method gave reproducible results and took only 20 minutes to perform. The dose of radiation to the mother was less than 1 mrad.

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