Department of Obstetrics and Gynaecology, Jessop Hospital for Women, Sheffield.
CIRCULATING LEVELS OF PREGNANCY-SPECIFIC β1-GLYCOPROTEIN IN EARLY PREGNANCY
Article first published online: 23 AUG 2005
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 84, Issue 10, pages 740–742, October 1977
How to Cite
Grudzinskas, J. G., Lenton, E. A., Gordon, Y. B., KELSO, I. M., Jeffrey, D., Sobowale, O. and Chard, T. (1977), CIRCULATING LEVELS OF PREGNANCY-SPECIFIC β1-GLYCOPROTEIN IN EARLY PREGNANCY. BJOG: An International Journal of Obstetrics & Gynaecology, 84: 740–742. doi: 10.1111/j.1471-0528.1977.tb12483.x
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
Circulating levels of pregnancy-specific β1-glycoprotein (SP1 or PSβG), luteinizing hormone (LH) and human chorionic gonadotrophin (HCG) were measured serially in 9 subjects immediately after conception. Ovulation occurred spontaneously in 3 subjects, or followed administration of clomiphene citrate (2 subjects) or bromocriptine (4 subjects). The timing of ovulation was determined by the appearance of the LH surge. Levels of HCG were detected 10 to 16 days, and SP1, 18 to 23 days after ovulation. These findings suggest that the measurement of plasma levels of SP1 may provide valuable additional biochemical evidence of pregnancy.