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RELATION BETWEEN CORTICOSTEROID AND ALBUMIN CONCENTRATIONS IN UMBILICAL VEIN PLASMA AND THE DURATION OF LABOUR
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1977.tb12553.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 84, Issue 3, pages 186–190, March 1977
Additional Information
How to Cite
Isherwood, D. M. (1977), RELATION BETWEEN CORTICOSTEROID AND ALBUMIN CONCENTRATIONS IN UMBILICAL VEIN PLASMA AND THE DURATION OF LABOUR. BJOG: An International Journal of Obstetrics & Gynaecology, 84: 186–190. doi: 10.1111/j.1471-0528.1977.tb12553.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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Summary
The concentration of corticosteroids in the umbilical vein plasma of babies delivered after a spontaneous onset of labour showed a significant positive correlation with the duration of labour (r = 0·593; P<0·001) and the length of the second stage (r = 0·48; P<0·02). Similar results were also obtained for induced labours. For labours of both induced and spontaneous onset, the albumin concentration in cord plasma also correlated significantly (r = 0·46; P<0·01) with the corticosteroid concentration. It is concluded that the stress of labour and vaginal delivery, and possibly changes in the concentration of proteins which bind corticosteroids, are important in determining the corticosteroid concentration in cord plasma obtained after delivery of the baby. The significance of these findings in relation to mechanisms responsible for the onset of human labour is discussed.