THE EFFECT OF ALTERING THYROID HORMONE CONCENTRATIONS ON PLASMA GONADOTROPHINS IN POSTMENOPAUSAL WOMEN
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1977.tb12572.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 84, Issue 4, pages 254–257, April 1977
Additional Information
How to Cite
Taylor, M. A. R., Chapman, C. and Hayter, C. J. (1977), THE EFFECT OF ALTERING THYROID HORMONE CONCENTRATIONS ON PLASMA GONADOTROPHINS IN POSTMENOPAUSAL WOMEN. BJOG: An International Journal of Obstetrics & Gynaecology, 84: 254–257. doi: 10.1111/j.1471-0528.1977.tb12572.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
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Summary
Plasma gonadotrophin levels were measured at frequent intervals in six post-menopausal thyrotoxic women treated with carbimazole. All patients showed an increasing follicle stimulating hormone/luteinizing hormone (FSH/LH) ratio as the thyroid hormone concentrations fell to normal and then into the hypothyroid range. Although the increased FSH/LH ratio was primarily due to a rise of FSH, two patients had a rise of both gonadotrophins. It is suggested that menstrual irregularities occurring in premenopausal women with disorders of thyroid metabolism may be related to similar changes.

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