AMNIOTIC FLUID LECITHIN/SPHINGOMYELIN RATIO IN PREGNANCY COMPLICATED BY DIABETES

  1. G. W. Dahlenburg,
  2. F. I. R. Martin,
  3. P. E. Jeffrey,
  4. I. Horacek

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1977.tb12580.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 84, Issue 4, pages 294–299, April 1977

Additional Information

How to Cite

Dahlenburg, G. W., Martin, F. I. R., Jeffrey, P. E. and Horacek, I. (1977), AMNIOTIC FLUID LECITHIN/SPHINGOMYELIN RATIO IN PREGNANCY COMPLICATED BY DIABETES. BJOG: An International Journal of Obstetrics & Gynaecology, 84: 294–299. doi: 10.1111/j.1471-0528.1977.tb12580.x

Author Information

  1. Diabetic Clinic and the Biochemistry Department Royal Women's Hospital, Melbourne

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005

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Summary

The lecithin/sphingomyelin (L/S) ratio in the amniotic fluid of 57 patients attending an antenatal diabetic clinic was determined. The L/S ratio in Class A, B and C patients (White, 1965) showed a similar rise with gestation to non-diabetic patients; 89 per cent in this group had an L/S ratio above 2:1, but of these 27 per cent developed mild or moderate respiratory distress syndrome (RDS). In Class D, F and R diabetic patients there was a little correlation of the L/S ratio with gestational age and in this group 55 per cent of the infants developed some form of RDS. The value of measuring amniotic fluid L/S ratios in the diabetic pregnancy is questioned.

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