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CORRELATION BETWEEN THROMBOPLASTIC ACTIVITY AND LECITHIN/SPHINGOMYELIN RATIO IN AMNIOTIC FLUID PRELIMINARY REPORT
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1977.tb12598.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 84, Issue 5, pages 354–356, May 1977
Additional Information
How to Cite
Yaffe, H., Bar-On, H., Eldor, A., Ron, M. and Sadovsky, E. (1977), CORRELATION BETWEEN THROMBOPLASTIC ACTIVITY AND LECITHIN/SPHINGOMYELIN RATIO IN AMNIOTIC FLUID PRELIMINARY REPORT. BJOG: An International Journal of Obstetrics & Gynaecology, 84: 354–356. doi: 10.1111/j.1471-0528.1977.tb12598.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
The thromboplastic activity of amniotic fluid was correlated with the lecithin sphingomyelin (L/S) ratio in 59 pregnancies. It was shown that the thromboplastic activity and the L/S ratio in amniotic fluid had a coefficient of correlation of r =−0.73 (P<0.004). The thromboplastic activity was estimated by a modified method for prothrombin time, and a time of 113 seconds appeared to correspond to an L/S ratio of 2, in that it was the borderline between maturity and immaturity of the fetal lungs. Thirty women were delivered within 24 hours of a sample of amniotic fluid being obtained. In the three patients whose babies developed the respiratory distress syndrome, the thromboplastic activity was estimated as being slower than 113 seconds.