Department of Obstetrics and Gynaecology, R. C. Hospital Sittard, The Netherlands.
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POLYCYSTIC OVARIAN DISEASE: DIAGNOSIS, FREQUENCY AND SYMPTOMS IN A GENERAL GYNAECOLOGICAL PRACTICE
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1977.tb12603.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 84, Issue 5, pages 380–385, May 1977
Additional Information
How to Cite
Declercq, J. A. and van de Calseyde, J. F. (1977), POLYCYSTIC OVARIAN DISEASE: DIAGNOSIS, FREQUENCY AND SYMPTOMS IN A GENERAL GYNAECOLOGICAL PRACTICE. BJOG: An International Journal of Obstetrics & Gynaecology, 84: 380–385. doi: 10.1111/j.1471-0528.1977.tb12603.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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- Cited By
Summary
A study was undertaken to assess the relative frequency of polycystic ovarian disease (POD) among patients with menstrual irregularities and/or hirsutism, and was based on 24-hour urinary steroid profiles under basal conditions, after dexamethasone suppression and after human chorionic gonadotrophin (HCG) stimulation. The final diagnosis was confirmed by laparoscopy or laparotomy and ovarian histology. Fifty-six patients were studied, 38 (68 per cent) of whom had POD. Laboratory results were subjected to multivariate discriminant analysis and a discriminant function was calculated to classify patients into POD and non-POD subgroups. Steroid profiling under basal conditions was sufficient to classify most of the patients into one of three groups: normal, POD, and other endocrinopathies. Of the patients with POD, 70 per cent had an abnormal reaction to dexamethasone or HCG. Significant differences were found in the steroid profiles of ovulating and non ovulating patients with POD.