THE EFFECT OF INTRAUTERINE FETAL TRANSFUSION AND A β-SYMPATHOMIMETIC SUBSTANCE ON THE LECITHIN/ SPHINGOMYELIN RATIO IN HUMAN AMNIOT1C FLUID

  1. B. Van Iddekinge Senior Lecturer1,
  2. Elizabeth A. Hughes Senior Biochemist and Honorary Senior Lecturer2

Article first published online: 28 JUN 2008

DOI: 10.1111/j.1471-0528.1977.tb12678.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 84, Issue 9, pages 669–673, September 1977

Additional Information

How to Cite

Van Iddekinge, B. and Hughes, E. A. (1977), THE EFFECT OF INTRAUTERINE FETAL TRANSFUSION AND A β-SYMPATHOMIMETIC SUBSTANCE ON THE LECITHIN/ SPHINGOMYELIN RATIO IN HUMAN AMNIOT1C FLUID. BJOG: An International Journal of Obstetrics & Gynaecology, 84: 669–673. doi: 10.1111/j.1471-0528.1977.tb12678.x

Author Information

  1. 1

    Institute of Obstetrics and Gynaecology, Hammersmith Hospital, W12 OHS

  2. 2

    Department of Paediatrics and Neonatal Medicine, Institute of Child Health Hammersmith Hospital, W12 OHS

Publication History

  1. Issue published online: 28 JUN 2008
  2. Article first published online: 28 JUN 2008

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Summary

The apparently low incidence of respiratory distress syndrome in babies born prematurely after irstrauterine transfusion and the simultaneous prophylactic administration of intravenous isoxsuprine (a β-sympathomimetic agent) was investigated by serial study of amniotic fluid lecithin/sphingomyelin ratios. The ratio rose very significantly after intrauterine transfusions and significantly (but less markedly) after the administration of intravenous isoxsuprine alone.

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