INDUCTION OF LABOUR BY PHARMACOLOGICAL AND PHYSIOLOGICAL DOSES OF INTRAVENOUS OXYTOCIN
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1978.tb10461.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 85, Issue 2, pages 101–108, February 1978
Additional Information
How to Cite
Toaff, M. E., Hezroni, J. and Toaff, R. (1978), INDUCTION OF LABOUR BY PHARMACOLOGICAL AND PHYSIOLOGICAL DOSES OF INTRAVENOUS OXYTOCIN. BJOG: An International Journal of Obstetrics & Gynaecology, 85: 101–108. doi: 10.1111/j.1471-0528.1978.tb10461.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
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Summary
In addition to membrane rupture, pharmacological doses of oxytocin (2·6 mU/ minute rising stepwise to 422·4 mU/minute) were used in 134 patients and the results compared to those obtained in 144 patients given only physiological doses of oxytocin (2·6 to 13·2 mU/minute). Pharmacological doses of oxytocin gave better results in terms of induction-delivery intervals, incidence of failed inductions and puerperal morbidity. The incidence of hypertonus was similar in both groups and unrelated to oxytocin doses. A uterine activity of 276 Montevideo units, modified to 200 to 220 Montevideo units for grande multiparae, is defined as the goal of oxytocin treatment in induction of labour. A sign of imminent uterine tetany in the intrauterine pressure curve (the ‘damping sign’) is described.

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